Proton MR spectroscopy in clinical routine
نویسندگان
چکیده
منابع مشابه
Clinical applications of proton MR spectroscopy.
Magnetic resonance (MR) spectroscopy has received little attention from the clinical radiology community. Indeed, most MR spectroscopic studies are performed by a small and dedicated group of individuals, mostly basic scientists. This behavior is partly because MR spectroscopy does not produce “pictures” but results in “graphs,” and until lately, it could only be obtained with dedicated units a...
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Nuclear magnetic resonance spectroscopy (MRS) has been in use in biochemistry labs for more than 50 yr. In its earlier years, it was used primarily for in vitro chemical analysis of small samples. Magnetic resonance imaging (MRI) is a powerful imaging technique that combines exquisite sensitivity to soft tissue contrast with the ability to demonstrate anatomy in many different planes and projec...
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PURPOSE To determine the contribution of MR spectroscopy in the assessment of childhood neurodegenerative disease. METHODS Fifty-one subjects (7 weeks to 17 years of age), 22 with either hereditary (n = 16) or acquired (n = 6) neurodegenerative disorders and 29 age-matched control subjects, were studied with combined proton MR spectroscopy and MR imaging. Single-voxel (2.0-8.0 cc) MR spectra ...
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A large body of published work shows that proton (hydrogen 1 [(1)H]) magnetic resonance (MR) spectroscopy has evolved from a research tool into a clinical neuroimaging modality. Herein, the authors present a summary of brain disorders in which MR spectroscopy has an impact on patient management, together with a critical consideration of common data acquisition and processing procedures. The art...
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In vivo proton spectra for four patients with Lesch-Nyhan disease and four control subjects matched for age and sex were acquired from voxels (1.5 x 1.5 x 1.5 cm3) placed in the prefrontal cortex and striatum. The patients with Lesch-Nyhan disease had decreased metabolites, especially N-acetylaspartate and glutamate/glutamine, only in the prefrontal cortex as compared with the control group. Th...
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ژورنال
عنوان ژورنال: Journal of Magnetic Resonance Imaging
سال: 2001
ISSN: 1053-1807
DOI: 10.1002/jmri.1079